The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 2017

Filed:

Mar. 15, 2013
Applicant:

Wake Forest University Health Sciences, Winston-Salem, NC (US);

Inventors:

William D. Wagner, Clemmons, NC (US);

Nicole Levi, Winston-Salem, NC (US);

Tabitha Rosenbalm, Winston-Salem, NC (US);

Louis C. Argenta, Winston-Salem, NC (US);

Michael J. Morykwas, Winston-Salem, NC (US);

Assignee:

WAKE FOREST UNIVERSITY HEALTH SCIENCES, Winston-Salem, NC (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61B 17/11 (2006.01); A61L 27/18 (2006.01); A61L 27/44 (2006.01); A61L 27/50 (2006.01); A61F 2/00 (2006.01); A61L 27/26 (2006.01); A61L 27/58 (2006.01); C08G 63/12 (2006.01); C08G 63/47 (2006.01); H01B 1/12 (2006.01); A61B 17/00 (2006.01);
U.S. Cl.
CPC ...
A61B 17/1128 (2013.01); A61F 2/0077 (2013.01); A61L 27/18 (2013.01); A61L 27/26 (2013.01); A61L 27/446 (2013.01); A61L 27/50 (2013.01); A61L 27/58 (2013.01); C08G 63/12 (2013.01); C08G 63/47 (2013.01); H01B 1/125 (2013.01); A61B 2017/00004 (2013.01); A61B 2017/00831 (2013.01); A61B 2017/00991 (2013.01); A61B 2017/1132 (2013.01); A61L 2400/12 (2013.01); A61L 2430/32 (2013.01);
Abstract

A biphasic material and devices comprising the same are provided for the development of conductive conduits that may be used for the treatment of peripheral nerve injury. These devices or conduits are designed such that repeated electric field gradients can be initiated to promote neurite and axonal outgrowth. Conducting conduits using doped synthetic and/or natural polymers create specifically patterned high and low conducting segmented materials, which are mechanically used to produce the electrical properties needed for nerve conduits. These electrical properties stimulate neurite outgrowth and axonal repair following a peripheral nerve transection.


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