The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2017
Filed:
Mar. 24, 2015
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Assignee:
Board of Regents, The University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/00 (2006.01); C07K 14/00 (2006.01); C07K 14/435 (2006.01); C07K 14/46 (2006.01); C07K 14/47 (2006.01); C07K 14/81 (2006.01); C07K 14/82 (2006.01); C07K 16/00 (2006.01); C07K 16/18 (2006.01); C07K 16/42 (2006.01); G01N 33/68 (2006.01); C07K 16/44 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6872 (2013.01); C07K 14/4702 (2013.01); C07K 14/82 (2013.01); C07K 16/18 (2013.01); C07K 16/44 (2013.01); G01N 33/57484 (2013.01); G01N 2440/14 (2013.01); G01N 2800/52 (2013.01);
Abstract
Antibodies specific for human Beclin 1 protein phosphorylated Ser234, Ser295, Tyr229, Tyr233 or Try352 are useful in diagnosing diseases such as cancer and impaired autophagy. The invention further relates to human Beclin 1 mutated at Ser234, Ser295, Tyr229, Tyr233 or Try352 with a phospho-silencing residue and uses thereof.