The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 06, 2017

Filed:

Mar. 24, 2014
Applicant:

Biocept, Inc., San Diego, CA (US);

Inventors:

Stephen D. Mikolajczyk, San Diego, CA (US);

Tony Pircher, San Diego, CA (US);

Farideh Z. Bischoff, Sugar Land, TX (US);

Pavel Tsinberg, Carlsbad, CA (US);

Assignee:

BIOCEPT, INC., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); G01N 33/543 (2006.01); G01N 33/569 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57492 (2013.01); C12Q 1/6886 (2013.01); G01N 33/54306 (2013.01); G01N 33/56966 (2013.01); G01N 33/57415 (2013.01); G01N 33/57423 (2013.01); G01N 33/57434 (2013.01); G01N 33/57446 (2013.01); G01N 33/57496 (2013.01); C12Q 2600/156 (2013.01); G01N 2333/4742 (2013.01); G01N 2333/71 (2013.01);
Abstract

The present invention provides a device for isolating target biomolecules or cells from samples, particularly biological samples. In particular, the device comprises a loading mixture, which contains the biological sample and a first binding entity that specifically binds to the target biomolecule or target cell; and a micro-channel coated with a second binding entity that binds directly or indirectly to the first binding entity. Methods of capturing, detecting, and/or evaluating target biomolecules or target cells (e.g. cancer cells) in biological samples are also disclosed.


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