The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2017
Filed:
Sep. 02, 2011
Applicants:
Vikas B. Palhan, St. Louis, MO (US);
Carol Kreader, St. Louis, MO (US);
Ernie Mueller, St. Louis, MO (US);
Inventors:
Vikas B. Palhan, St. Louis, MO (US);
Carol Kreader, St. Louis, MO (US);
Ernie Mueller, St. Louis, MO (US);
Assignee:
SIGMA-ALDRICH CO., LLC, St. Louis, MO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 1/44 (2006.01); C12N 1/20 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5308 (2013.01); C12N 1/20 (2013.01); G01N 1/44 (2013.01); G01N 33/6803 (2013.01); G01N 33/6875 (2013.01);
Abstract
The present invention provides isolated, non-viable bacterial cells comprising a plurality of nucleic acid crosslinks, methods for making said cells, and methods for using said cells to isolate DNA-protein complexes. In particular, the nucleic acids of the cells are crosslinked by contacting the cells with a furocoumarin compound and ultraviolet light.