The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 06, 2017

Filed:

Feb. 10, 2014
Applicant:

Japanese Foundation for Cancer Research, Tokyo, JP;

Inventors:

Eiji Hara, Tokyo, JP;

Naoko Ohtani, Tokyo, JP;

Shin Yoshimoto, Tokyo, JP;

Tze Mun Loo, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/574 (2006.01); A61K 31/4164 (2006.01); A61K 31/43 (2006.01); A61K 31/496 (2006.01); A61K 31/7036 (2006.01); C12Q 1/02 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); A61K 31/4164 (2013.01); A61K 31/43 (2013.01); A61K 31/496 (2013.01); A61K 31/7036 (2013.01); C12Q 1/025 (2013.01); C12Q 1/689 (2013.01); G01N 33/57484 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/33 (2013.01); G01N 2500/10 (2013.01);
Abstract

The present invention provides a method capable of detecting a cancer and/or a carcinogenic risk, and a reagent for the detection thereof. The present invention also provides a method for screening for a pharmaceutical drug for reducing a carcinogenic risk and a pharmaceutical composition. Since cancer development closely correlates with alteration in gut microbiota, cancer development and/or a risk of cancer development are detected by detecting alteration in gut microbiota and a secondary bile acid produced by an intestinal bacterium. The present invention further provides a method for screening for a pharmaceutical drug with a gut microbiota as an index, and a pharmaceutical composition.


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