The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 06, 2017

Filed:

Jun. 28, 2012
Applicants:

Bert Vogelstein, Balitmore, MD (US);

Kenneth W. Kinzler, Baltimore, MD (US);

Nickolas Papadopoulos, Towson, MD (US);

Jian Wu, Baltimore, MD (US);

Inventors:

Bert Vogelstein, Balitmore, MD (US);

Kenneth W. Kinzler, Baltimore, MD (US);

Nickolas Papadopoulos, Towson, MD (US);

Jian Wu, Baltimore, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6806 (2013.01); C12Q 1/6806 (2013.01); C12Q 2535/122 (2013.01); C12Q 2563/131 (2013.01); C12Q 2563/149 (2013.01); C12Q 2565/518 (2013.01);
Abstract

Assays can be used to detect mutations found in neoplasms of the pancreas, as well as for other neoplasms and other uses. Nucleic acids can be captured from body fluids such as cyst fluids. Thousands of oligonucleotides can be synthesized in parallel, amplified and ligated together. The ligated products can be further amplified. The amplified, ligated products are used to capture complementary DNA sequences, which can be analyzed, for example by massively parallel sequencing.


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