The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2017
Filed:
May. 09, 2012
Applicant:
Adam Meadows, Emeryville, CA (US);
Inventor:
Adam Meadows, Emeryville, CA (US);
Assignee:
Amyris Inc., Emeryville, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/62 (2006.01); C12N 1/38 (2006.01); C12N 15/52 (2006.01); C12P 17/06 (2006.01); C12P 7/64 (2006.01); C12P 13/04 (2006.01); C12P 5/00 (2006.01);
U.S. Cl.
CPC ...
C12P 19/62 (2013.01); C12N 1/38 (2013.01); C12N 15/52 (2013.01); C12P 5/007 (2013.01); C12P 7/6409 (2013.01); C12P 7/6427 (2013.01); C12P 13/04 (2013.01); C12P 17/06 (2013.01);
Abstract
The present disclosure relates to the use of pantothenate compounds as a non-genetic switch for the production of heterologous acetyl-CoA derived (HACD) compounds in microbial host cells. The invention provides genetically modified microorganisms that are more stable when stored and initially cultured under reduced pantothenate concentrations, cell culture media having reduced concentrations of pantothenate compounds, and methods of producing HACD compounds using the cell culture media and the genetically engineered microorganisms of the invention.