The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2017
Filed:
Mar. 26, 2015
Applicant:
Universitat Leipzig, Leipzig, DE;
Inventor:
Peter Seibel, Uettingen, DE;
Assignee:
UNIVERSITAT LEIPZIG, Leipzig, DE;
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/02 (2006.01); C12N 5/00 (2006.01); C12N 15/00 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); C12N 2800/107 (2013.01); C12N 2820/60 (2013.01);
Abstract
The invention relates to a mitochondrial expression vector which may comprise a gene to be expressed and/or a selection marker and a mitochondrial region, and a method for inserting a DNA to be expressed into mitochondria of mammalian cells, wherein the method may comprise the steps: (i) construction of a mitochondrial expression vector or a mitochondrial genome, (ii) reversible induction of megamitochondria and (iii) transfection of the megamitochondria by means of a physical transfection method.