The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2017
Filed:
Aug. 09, 2011
Applicants:
Katsuyuki Dodo, Otsu, JP;
Hideto Chono, Otsu, JP;
Junichi Mineno, Otsu, JP;
Inventors:
Assignee:
TAKARA BIO INC., Shiga, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C12N 5/00 (2006.01); C12N 5/18 (2006.01); C12N 5/0783 (2010.01); A61K 35/17 (2015.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0636 (2013.01); A61K 35/17 (2013.01); C12N 5/0637 (2013.01); A61K 35/12 (2013.01); C12N 2501/2304 (2013.01); C12N 2501/998 (2013.01); C12N 2510/00 (2013.01);
Abstract
The present invention addresses the problem of providing cell populations having a high proportion of CD4-positive naive T cells and/or CD4-positive central memory T cells, and a production method thereof. The present invention provides a production method for CD4-positive T cell populations which is characterized by using anti-CD3 antibodies, fibronectin fragments, and Interleukin-4. The method is characterized not only by the attainment of a cell group with a high proportion of CD4-positive naive T cells and/or CD4-positive central memory T cells, but also by a high bulk yield.