The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 06, 2017

Filed:

Jun. 19, 2013
Applicants:

Baxalta Gmbh, Opfikon, CH;

Baxalta Incorporated, Bannockburn, IL (US);

Inventors:

Wolfgang Mundt, Vienna, AT;

Artur Mitterer, Orth/Donau, AT;

Manfred Reiter, Vienna, AT;

Meinhard Hasslacher, Vienna, AT;

Leopold Grillberger, Vienna, AT;

Thomas Kreil, Klosterneuburg, AT;

Assignees:

BAXALTA GMBH, Opfikon, CH;

BAXALTA INCORPORATED, Bannockburn, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/02 (2006.01); C12N 5/071 (2010.01); A61L 2/00 (2006.01); C12M 1/00 (2006.01); C12M 1/12 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0602 (2013.01); A61L 2/0017 (2013.01); C12M 29/26 (2013.01); C12M 37/02 (2013.01);
Abstract

The invention relates to a method for removing a viral contaminant from a preparation, being a cell culture medium or at least a component of a cell culture medium. The method comprises subjecting said preparation to filtration for at least about 24 hours through a virus filter having an effective pore size of maximum about 75 nm. Further, the invention relates to the use of a virus filter in filtration of at least about 24 hours, wherein the virus filter has an effective pore size of maximum about 75 nm for the removal of viral contaminant from a preparation, being a cell culture medium or at least a component of a cell culture medium. In some embodiments the filtration according to the invention operates at a volumetric capacity of at least about 2000 L/m. Further, the invention relates to the use of a preparation, being a cell culture medium or at least a component of a cell culture medium obtainable according to method of the invention for cell culture; pharmaceutical, diagnostic and/or cosmetic preparations as well as in food preparations.


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