The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 06, 2017

Filed:

Apr. 20, 2016
Applicant:

The Arizona Board of Regents on Behalf of the University of Arizona, Tucson, AZ (US);

Inventors:

Meredith Hay, Tucson, AZ (US);

John Konhilas, Tucson, AZ (US);

Robin L. Polt, Tucson, AZ (US);

Evan Jones, Tucson, AZ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/14 (2006.01); C07K 7/06 (2006.01); C07K 7/00 (2006.01); A61K 38/00 (2006.01); C07K 9/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/14 (2013.01); C07K 7/06 (2013.01); C07K 9/001 (2013.01); A61K 38/00 (2013.01);
Abstract

The present invention provides oligopeptides, in particular, Ang-(1-7) derivatives, and methods for using and producing the same. In one particular embodiment, oligopeptides of the invention have higher blood-brain barrier penetration and/or in vivo half-life compared to the native Ang-(1-7), thereby allowing oligopeptides of the invention to be used in a wide variety of clinical applications including in treatment of cognitive dysfunction and/of impairment.


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