The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2017
Filed:
May. 09, 2016
Applicant:
Takeda Pharmaceutical Company Limited, San Diego, CA (US);
Inventors:
Stephen Hitchcock, San Diego, CA (US);
Holger Monenschein, San Diego, CA (US);
Holly Reichard, San Diego, CA (US);
Huikai Sun, San Diego, CA (US);
Shota Kikuchi, San Diego, CA (US);
Todd Macklin, San Diego, CA (US);
Maria Hopkins, San Diego, CA (US);
Assignee:
Takeda Pharmaceutical Company Limited, Osaka, JP;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 519/00 (2006.01); C07D 498/08 (2006.01); C07D 471/04 (2006.01); C07D 451/12 (2006.01); C07D 221/22 (2006.01); A61K 31/19 (2006.01); A61K 31/5386 (2006.01); C07C 53/40 (2006.01); C07D 453/02 (2006.01); C07D 471/08 (2006.01); C07C 53/18 (2006.01);
U.S. Cl.
CPC ...
C07D 498/08 (2013.01); A61K 31/19 (2013.01); A61K 31/5386 (2013.01); C07C 53/18 (2013.01); C07C 53/40 (2013.01); C07D 221/22 (2013.01); C07D 451/12 (2013.01); C07D 453/02 (2013.01); C07D 471/04 (2013.01); C07D 471/08 (2013.01); C07D 519/00 (2013.01);
Abstract
The present invention provides 5-HT3 receptor antagonists of Formula (I): which are useful for the treatment of diseases treatable by inhibition of 5-HT3 receptor such as emesis, pain, drug addiction, neurodegenerative and psychiatric disorders, and GI disorders. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.