The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 06, 2017

Filed:

May. 28, 2015
Applicant:

Vertex Pharmaceuticals Incorporated, Boston, MA (US);

Inventors:

Nadia Ahmad, Didcot, GB;

Jean-Damien Charrier, Wantage, GB;

Chris Davis, Salisbury, GB;

Gorka Etxebarria I Jardi, Abingdon, GB;

Damien Fraysse, Abingdon, GB;

Ronald Knegtel, Abingdon, GB;

Maninder Panesar, Didcot, GB;

Francoise Pierard, Abingdon, GB;

Joanne Pinder, Didcot, GB;

Pierre-Henri Storck, Abingdon, GB;

John Studley, Witney, GB;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01);
Abstract

The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and solid forms of the compounds of this invention. The compounds of this invention have formula I-1 or I-A: wherein the variables are as defined herein.


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