The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 06, 2017

Filed:

Dec. 18, 2014
Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Thomas A. Miller, Wakefield, MA (US);

Alessia Petrocchi, Houston, TX (US);

Eric T. Romeo, Allston, MA (US);

Dilrukshi Vitharana, Somerville, MA (US);

Solomon D. Kattar, Arlington, MA (US);

Alan B. Northrup, Reading, MA (US);

Michael D. Altman, Needham, MA (US);

Neville J. Anthony, Northborough, MA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 413/12 (2006.01); C07D 471/04 (2006.01); C07D 491/048 (2006.01); C07D 495/04 (2006.01); A61K 31/437 (2006.01); A61K 31/444 (2006.01); A61K 31/517 (2006.01); A61K 31/519 (2006.01);
U.S. Cl.
CPC ...
C07D 417/12 (2013.01); A61K 31/437 (2013.01); A61K 31/444 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); C07D 471/04 (2013.01); C07D 491/048 (2013.01); C07D 495/04 (2013.01); C07D 413/12 (2013.01); C07D 417/14 (2013.01);
Abstract

The invention provides certain thiazole-substituted aminoheteroaryl compounds of the Formula (I) (I), or pharmaceutically acceptable salts thereof, wherein ring R, R, R, R, ring A, and the subscripts n1, n2, and r are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).


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