The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 06, 2017

Filed:

May. 09, 2014
Applicant:

Merck Patent Gmbh, Darmstadt, DE;

Inventors:

Christos Tsaklakidis, Weinheim, DE;

Wolfgang Staehle, Ingelheim, DE;

Birgitta Leuthner, Darmstadt, DE;

Paul Czodrowski, Friedberg, DE;

Thomas Fuchss, Bensheim-Auerbach, DE;

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 233/79 (2006.01); C07D 413/14 (2006.01); C07D 309/04 (2006.01); C07D 215/12 (2006.01); C07D 317/50 (2006.01); C07D 319/18 (2006.01); C07D 231/12 (2006.01); C07D 231/56 (2006.01); C07D 233/26 (2006.01); C07D 401/04 (2006.01); C07D 235/06 (2006.01); C07D 235/18 (2006.01); C07D 235/26 (2006.01); C07D 403/04 (2006.01); C07D 413/04 (2006.01); C07D 413/12 (2006.01); C07D 417/04 (2006.01); C07D 249/18 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 263/57 (2006.01); C07D 498/04 (2006.01); C07D 209/08 (2006.01); C07D 209/14 (2006.01); C07D 277/62 (2006.01); C07D 277/66 (2006.01); C07D 209/30 (2006.01); C07D 209/34 (2006.01); C07D 209/42 (2006.01); C07D 213/56 (2006.01); C07C 255/57 (2006.01); C07C 235/42 (2006.01); A61K 31/166 (2006.01); A61K 31/277 (2006.01); A61K 31/4164 (2006.01); A61K 31/4184 (2006.01); A61K 31/423 (2006.01); A61K 31/428 (2006.01); A61K 31/451 (2006.01); A61K 31/501 (2006.01); A61K 31/519 (2006.01); C07C 231/10 (2006.01); C07C 253/30 (2006.01); C07C 255/60 (2006.01); C07D 233/58 (2006.01);
U.S. Cl.
CPC ...
C07C 233/79 (2013.01); A61K 31/166 (2013.01); A61K 31/277 (2013.01); A61K 31/4164 (2013.01); A61K 31/4184 (2013.01); A61K 31/423 (2013.01); A61K 31/428 (2013.01); A61K 31/451 (2013.01); A61K 31/501 (2013.01); A61K 31/519 (2013.01); C07C 231/10 (2013.01); C07C 235/42 (2013.01); C07C 253/30 (2013.01); C07C 255/57 (2013.01); C07C 255/60 (2013.01); C07D 209/08 (2013.01); C07D 209/14 (2013.01); C07D 209/30 (2013.01); C07D 209/34 (2013.01); C07D 209/42 (2013.01); C07D 213/56 (2013.01); C07D 215/12 (2013.01); C07D 231/12 (2013.01); C07D 231/56 (2013.01); C07D 233/26 (2013.01); C07D 233/58 (2013.01); C07D 235/06 (2013.01); C07D 235/18 (2013.01); C07D 235/26 (2013.01); C07D 249/18 (2013.01); C07D 263/57 (2013.01); C07D 277/62 (2013.01); C07D 277/66 (2013.01); C07D 309/04 (2013.01); C07D 317/50 (2013.01); C07D 319/18 (2013.01); C07D 401/04 (2013.01); C07D 403/04 (2013.01); C07D 413/04 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/04 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 498/04 (2013.01); C07C 2101/02 (2013.01); C07C 2101/08 (2013.01); C07C 2101/14 (2013.01);
Abstract

Compounds of the formula I in which R, R, R, R, X, X, X, X, q and W have the meanings indicated in claimare inhibitors of fatty acid synthase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.


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