The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 06, 2017

Filed:

Nov. 18, 2015
Applicant:

Cem Corporation, Matthews, NC (US);

Inventors:

Jonathan McKinnon Collins, Charlotte, NC (US);

Joseph Joshua Lambert, Charlotte, NC (US);

Michael John Collins, Charlotte, NC (US);

Assignee:

CEM CORPORATION, Matthews, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); B01J 19/12 (2006.01); C07K 1/04 (2006.01); B01J 19/08 (2006.01); C07K 5/08 (2006.01); C07K 7/06 (2006.01); C07K 1/06 (2006.01);
U.S. Cl.
CPC ...
B01J 19/126 (2013.01); B01J 19/087 (2013.01); C07K 1/045 (2013.01); C07K 1/063 (2013.01); C07K 5/08 (2013.01); C07K 7/06 (2013.01); B01J 2219/0871 (2013.01); B01J 2219/0879 (2013.01); B01J 2219/126 (2013.01); B01J 2219/1206 (2013.01); B01J 2219/1209 (2013.01); B01J 2219/1215 (2013.01); B01J 2219/1218 (2013.01); B01J 2219/1221 (2013.01); B01J 2219/1254 (2013.01); B01J 2219/1272 (2013.01); B01J 2219/1293 (2013.01);
Abstract

An instrument and method for accelerating the solid phase synthesis of peptides are disclosed. The method includes the steps of deprotecting a protected first amino acid linked to a solid phase resin by admixing the protected linked acid with a deprotecting solution in a microwave transparent vessel while irradiating the admixed acid and solution with microwaves, activating a second amino acid, coupling the second amino acid to the first acid while irradiating the composition in the same vessel with microwaves, and cleaving the linked peptide from the solid phase resin by admixing the linked peptide with a cleaving composition in the same vessel while irradiating the composition with microwaves.


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