The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 06, 2017

Filed:

Oct. 26, 2011
Applicants:

Dae Seong Im, Yongin-si, KR;

Jae Min Lee, Seoul, KR;

Jong Soo Lee, Seongnam-si, KR;

Sung Min Bae, Seongnam-si, KR;

SE Chang Kwon, Seoul, KR;

Inventors:

Dae Seong Im, Yongin-si, KR;

Jae Min Lee, Seoul, KR;

Jong Soo Lee, Seongnam-si, KR;

Sung Min Bae, Seongnam-si, KR;

Se Chang Kwon, Seoul, KR;

Assignee:

HANMI SCIENCE CO., LTD., Hwaseong-si, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 38/21 (2006.01); A61K 47/26 (2006.01); A61K 47/48 (2006.01); C07K 14/56 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48415 (2013.01); A61K 9/0019 (2013.01); A61K 38/212 (2013.01); A61K 47/26 (2013.01); A61K 47/48369 (2013.01); A61K 47/48423 (2013.01); C07K 14/56 (2013.01); C07K 16/46 (2013.01); C07K 2319/30 (2013.01);
Abstract

Disclosed is a liquid formulation in which a long-acting INFα conjugate that has improved in vivo duration and stability can be stored stably for a long period of time. It comprises a stabilizer comprising a buffer, a sugar alcohol, a non-ionic surfactant and an isotonic agent. Being free of human serum albumin and other potential factors harmful to the body, the liquid formulation is free of concerns about viral infections and guarantees excellent storage stability to long-acting INFα conjugates.


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