The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2017
Filed:
Mar. 18, 2016
Korea National University of Transportation Industry-academic Cooperation Foundation, Chungcheongbuk-do, KR;
The Catholic University of Korea Industry-academic Cooperation Foundation, Seoul, KR;
Yong Kyu Lee, Chungcheongbuk-do, KR;
Sung Hoon Kang, Chungcheongbuk-do, KR;
Sang Joon Lee, Gwangju, KR;
In Kyu Park, Gwangju, KR;
Kwang Jae Cho, Seoul, KR;
Mohammed Nurunnabi, Chungcheongbuk-do, KR;
Abstract
Disclosed are a metal-nanoparticle-based liver-specific nucleic acid delivery system, a method of manufacturing the same, and a liver disease treatment composition containing the same. The liver-specific nucleic acid delivery system is coated with a bile acid-glycol chitosan polymer, so that it provides excellent liver-tissue specificity and high absorbance through digestive canals. Since the nucleic acid of the nucleic acid delivery system is coated with the bile acid-glycol chitosan polymer, it can be protected from decomposition of enzymes and the like inside a living organism. The liver-specific nucleic acid delivery system can be developed as an oral-administrating liver-disease treatment.