The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2017
Filed:
Dec. 20, 2013
Applicant:
Glaxosmithkline Biologicals S.a., Rixensart, BE;
Inventor:
Cindy Castado, Rixensart, BE;
Assignee:
GLAXOSMITHKLINE BIOLOGICALS S.A., Rixensart, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/08 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/08 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/6068 (2013.01);
Abstract
The present invention relates to immunogenic compositions comprising isolatedCDTb and/or CDTa protein. In particular the isolatedCDTb protein is suitably a truncated CDTb protein comprising the receptor binding domain or a mutated CDTb protein incapable of binding to CDTa, and the isolatedCDTa protein is suitably a truncated CDTa protein which does not comprise the C-terminal domain. In particular the invention also relates to fusion proteins comprising a CDTa protein and a CDTb protein and also fusion proteins between an isolatedtoxin A protein and/or an isolatedtoxin B protein fused to a CDTb protein.