The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 06, 2017

Filed:

May. 19, 2014
Applicants:

Jon Y. Takemoto, North Logan, UT (US);

Cheng-wei Tom Chang, Logan, UT (US);

Sanjib K. Shrestha, Lexington, KY (US);

Michelle Grilley, Logan, UT (US);

Inventors:

Jon Y. Takemoto, North Logan, UT (US);

Cheng-wei Tom Chang, Logan, UT (US);

Sanjib K. Shrestha, Lexington, KY (US);

Michelle Grilley, Logan, UT (US);

Assignee:

Utah State University, Logan, UT (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/7036 (2006.01); A61K 31/496 (2006.01); A61K 31/4196 (2006.01); A61K 31/506 (2006.01); A61K 31/415 (2006.01); A61K 31/365 (2006.01); A01N 43/16 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7036 (2013.01); A01N 43/16 (2013.01); A61K 31/365 (2013.01); A61K 31/415 (2013.01); A61K 31/4196 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01);
Abstract

The present invention relates to novel fungicidal compound including an aminoglycoside analog having certain substituents at the 6 position of ring III that exhibit improved antifungal activity but possess minimal antibacterial properties in combination with fungicidal azoles. The aminoglycoside compounds are analogues of kanamycin A. Also provided are methods of synthesizing and methods of using the compounds of the present invention. The compounds of the present invention are useful in treating or preventing fungal disease.


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