The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2017
Filed:
May. 14, 2014
Applicant:
The University of Chicago, Chicago, IL (US);
Inventors:
Assignee:
THE UNIVERSITY OF CHICAGO, Chicago, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/12 (2006.01); A61K 31/165 (2006.01); A61K 31/167 (2006.01); A61K 45/06 (2006.01); A61K 31/255 (2006.01); A61K 31/40 (2006.01); A61K 31/4192 (2006.01); A61K 31/4402 (2006.01); A61K 31/185 (2006.01); A61K 31/4045 (2006.01); A61K 31/436 (2006.01); A61K 31/4375 (2006.01); A61K 31/4406 (2006.01); A61K 31/4745 (2006.01); A61K 31/517 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 31/12 (2013.01); A61K 31/165 (2013.01); A61K 31/167 (2013.01); A61K 31/185 (2013.01); A61K 31/255 (2013.01); A61K 31/40 (2013.01); A61K 31/4045 (2013.01); A61K 31/4192 (2013.01); A61K 31/436 (2013.01); A61K 31/4375 (2013.01); A61K 31/4402 (2013.01); A61K 31/4406 (2013.01); A61K 31/4745 (2013.01); A61K 31/517 (2013.01); A61K 45/06 (2013.01);
Abstract
The disclosure relates to methods of controlling the state of a virus (lytic or lysogenic) in an individual, such as a method of reactivating a latent virus in an individual, comprising administering one or more agents that modulates the activity of signal transducer and activator of transcription 3 (STAT3) or any of p300, CBP or p300/CBP. Also contemplated are methods further comprising administering an HDAC modulating agent, such as an HDAC inhibiting agent or an HDAC activating agent.