The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2017
Filed:
Mar. 29, 2016
Applicant:
Northwestern University, Evanston, IL (US);
Inventors:
Teepu Siddique, Wilmette, IL (US);
Thomas J. Lukas, Evanston, IL (US);
Hasan Arrat, Chicago, IL (US);
Gary E. Schiltz, Naperville, IL (US);
Assignee:
Northwestern University, Evanston, IL (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/04 (2006.01); A61K 31/4439 (2006.01); C07D 413/14 (2006.01); C07D 271/113 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4439 (2013.01); C07D 413/04 (2013.01); C07D 271/113 (2013.01); C07D 413/14 (2013.01); C07D 417/04 (2013.01); C07D 417/14 (2013.01);
Abstract
Disclosed are new small molecules and the uses thereof for inhibiting superoxide dismutase (SOD) expression. Also disclosed are pharmaceutical compositions comprising the small molecule inhibitors which may be administered in methods of treating diseases or disorders associated with elevated SOD expression or activity, including neurological diseases and disorders such as amyotrophic lateral sclerosis (ALS).