The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2017
Filed:
Jan. 24, 2014
Peking University, Beijing, CN;
Wei Kong, Beijing, CN;
Qinghua Cui, Beijing, CN;
Jingang Zheng, Beijing, CN;
Ziyi Liu, Beijing, CN;
Fang Yu, Beijing, CN;
PEKING UNIVERSITY, Beijing, CN;
Abstract
Naringenin is used for preparing products for preventing and/or treating abdominal aortic aneurysms. The products include drugs and/or health care products. The products were tested in two clinically associated abdominal aortic aneurysm disease models: using angiotensin II (1000 ng/kg/min) through subcutaneous submerging pump to induce ApoE knockout mice; and using calcium phosphate (0.5 M) to daub the abdominal aortas of locally induced Cmice with abdominal aortic aneurysms. Experiments demonstrate that orally administered naringenin can significantly inhibit the onset and development of an abdominal aortic aneurysm in the CaPOdaubed and AngII submerging pump induced mice. Thus, naringenin can be used in the treatment of patients with abdominal aortic aneurysms.