The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2017
Filed:
Apr. 29, 2011
Nathalia Giese, Schriesheim, DE;
Jens Werner, Dossenheim, DE;
Markus Buechler, Heidelberg, DE;
Thomas Giese, Schriesheim, DE;
Laurent Daeffler, Heidelberg, DE;
Celina Czeipluch, Heidelberg, DE;
Jean Rommelaere, Heidelberg, DE;
Zahari Raykov, Heidelberg, DE;
Nathalia Giese, Schriesheim, DE;
Jens Werner, Dossenheim, DE;
Markus Buechler, Heidelberg, DE;
Thomas Giese, Schriesheim, DE;
Laurent Daeffler, Heidelberg, DE;
Celina Czeipluch, Heidelberg, DE;
Jean Rommelaere, Heidelberg, DE;
Zahari Raykov, Heidelberg, DE;
Deutsches Krebsforschungszentrum, Heidelberg, DE;
Ruprecht-Karls-Universitaet Heidelberg, Heidelberg, DE;
Universitaetsklinikum Heidelberg, Heidelberg, DE;
Abstract
Described is a diagnostic method for predicting the response of a patient to chemovirotherapy or radiovirotherapy, comprising exposing primary tumor cells from a patient, e.g., tumor cells obtained from a brain tumor or pancreatic cancer, to (i) a parvovirus and/or (ii) a chemotherapeutic agent or radiotherapy, and determining the reduction of the expression or concentration of ISG15.