The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 30, 2017

Filed:

Jan. 02, 2015
Applicant:

National Tsing Hua University, Hsinchu, TW;

Inventors:

Ting-Ju Yueh, Hsinchu, TW;

Chi-Fan Chen, Douliu, TW;

Kuo-Wei Chang, Zhudong Township, Hsinchu County, TW;

Pei-Yu Chang, Tainan, TW;

Cheng-Hsien Liu, Hsinchu, TW;

Hong-Yuan Huang, Taipei, TW;

Chin-Jung Li, Hsinchu, TW;

Chang-Hung Tien, New Taipei, TW;

Da-Jeng Yao, Hsinchu, TW;

Shih-Kang Fan, Taipei, TW;

Wen-Syang Hsu, Hsinchu, TW;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/00 (2006.01); C12M 3/00 (2006.01); C12M 3/06 (2006.01); C12M 1/12 (2006.01); C12M 1/32 (2006.01); C12M 1/42 (2006.01);
U.S. Cl.
CPC ...
C12M 23/34 (2013.01); C12M 21/06 (2013.01); C12M 21/08 (2013.01); C12M 23/04 (2013.01); C12M 23/12 (2013.01); C12M 23/16 (2013.01); C12M 23/58 (2013.01); C12M 29/10 (2013.01); C12M 35/08 (2013.01);
Abstract

The present disclosure illustrates a platform system for in vitro cell co-cultivation with automatic trapping function. The platform system aims to develop a bio-chip applied in cell culture systems, and has several features. The first feature is that this co-cultivation platform can construct a micro environment suitable for culture of various cells. The second feature is dynamic perfusion. The microfluidic system is used to dynamically replace the culture medium, in order to maintain an appropriate environment for the growth of cells. The third feature is the automatic trapping. The cells to be cultured can be trapped in a suitable location according to the flow resistance, so that the damaged on the cell caused by manual operation can be minimized.


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