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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9663558 B1

PDFFull Text
Date of Patent:
May. 30, 2017

Filed:

Jul. 10, 2014

Mutated immunoglobulin-binding polypeptides

Applicant:

GE Healthcare Bio-sciences Ab, Uppsala, SE;

Inventors:

Mats Ander, Uppsala, SE;

Goran Bauren, Uppsala, SE;

Tomas Bjorkman, Uppsala, SE;

Gustav Rodrigo, Uppsala, SE;

Assignee:

GE Healthcare Bio-Sciences AB, Uppsala, SE;

Attorney:

Wood IP LLC

Primary Examiner:

Maury Audet

Int. Cl.
CPC ...
C07K 14/31 (2006.01); C07K 1/22 (2006.01); B01D 15/38 (2006.01); B01J 20/286 (2006.01); B01J 20/32 (2006.01); C07K 14/745 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/31 (2013.01); B01D 15/3809 (2013.01); B01J 20/286 (2013.01); B01J 20/3204 (2013.01); B01J 20/3212 (2013.01); B01J 20/3219 (2013.01); B01J 20/3274 (2013.01); C07K 1/22 (2013.01); C07K 14/745 (2013.01); C07K 16/00 (2013.01);
Abstract

A polypeptide with improved alkaline stability, which polypeptide comprises a mutant of a B or C domain ofProtein A, as specified by SEQ ID NO 1 or SEQ ID NO 2, or of Protein Z, as specified by SEQ ID NO 3, wherein at least the glutamine residue at position 15 has been mutated to an amino acid other than asparagine. The invention also discloses multimers of the polypeptide, as well as separation matrices comprising the multimers or polypeptides.

Find Patent Forward Citations

Ander, Mats. (2017). Mutated immunoglobulin-binding polypeptides (U.S. Patent No. 9663558). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9663558

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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