The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2017
Filed:
Dec. 12, 2014
Applicant:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Inventors:
Pengcheng Patrick Shao, Fanwood, NJ (US);
Feng Ye, Scotch Plains, NJ (US);
Petr Vachal, Summit, NJ (US);
Assignee:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/04 (2006.01); C07D 231/54 (2006.01); C07D 413/04 (2006.01); C07D 413/10 (2006.01); C07D 413/12 (2006.01); A61K 31/423 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); A61K 45/06 (2006.01); C07D 261/20 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); A61K 31/423 (2013.01); A61K 31/444 (2013.01); A61K 31/4439 (2013.01); A61K 45/06 (2013.01); C07D 231/54 (2013.01); C07D 261/20 (2013.01); C07D 413/04 (2013.01); C07D 413/10 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01);
Abstract
Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, wherein X is (CH) or O, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis: