The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2017
Filed:
May. 07, 2015
Applicant:
Takeda Pharmaceutical Company Limited, Osaka, JP;
Inventors:
Mitsunori Kono, San Diego, CA (US);
Zhe Nie, San Diego, CA (US);
Assignee:
Takeda Pharmaceutical Company Limited, Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 519/00 (2006.01); A61K 31/4365 (2006.01); A61K 31/437 (2006.01); A61K 31/4985 (2006.01); A61K 31/519 (2006.01); A61K 31/5383 (2006.01); C07D 487/04 (2006.01); C07D 495/04 (2006.01); C07D 498/04 (2006.01); A61K 31/5365 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/437 (2013.01); A61K 31/4365 (2013.01); A61K 31/4985 (2013.01); A61K 31/519 (2013.01); A61K 31/5365 (2013.01); A61K 31/5383 (2013.01); C07D 487/04 (2013.01); C07D 495/04 (2013.01); C07D 498/04 (2013.01); C07D 519/00 (2013.01);
Abstract
Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein G, p, R, R, R, R, and Rare defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating disorders, diseases, and conditions involving the immune system and inflammation, including rheumatoid arthritis, cancer, and other disorders, diseases, and conditions for which inhibition of SYK is indicated.