The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2017
Filed:
Jul. 07, 2014
Dainippon Sumitomo Pharma Co., Ltd., Osaka, JP;
Izumi Sasaki, Chuo-ku, JP;
Tomohiro Toyoda, Suita, JP;
Hidefumi Yoshinaga, Suita, JP;
Itaru Natsutani, Suita, JP;
Yoko Takahashi, Osaka, JP;
SUMITOMO DAINIPPON PHARMA CO., LTD., Osaka, JP;
Abstract
The present invention relates to a novel serotonin reuptake inhibitor which also exhibits 5-HTantagonistic action (antidepressive and anxiolytic effects), in particular, 5-HTinverse agonistic action comprising Compound (1): or a pharmaceutically acceptable salt thereofwherein R, R, Rand Rare independently hydrogen or Calkyl etc.; Ris Calkyl or —(CRR)-E; R, R, Rand Rare independently hydrogen, fluorine or Calkyl; A is Caryl or heteroaryl etc.; r is 1, 2, 3 or 4; E is Ccycloalkyl or Caryl etc.; L is oxygen, sulfur or —NR—; n is 1, 2 or 3; Ris hydrogen or Calkyl etc.; and X is hydrogen or halogen etc.