The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 30, 2017

Filed:

Jul. 30, 2014
Applicants:

Les Laboratoires Servier, Suresnes, FR;

Shanghai Institute of Pharmaceutical Industry, Shanghai, CN;

Inventors:

Hanbin Shan, Gaoan, CN;

Yuhui Shen, Shanghai, CN;

Ying Luo, NanChang, CN;

Philippe Letellier, Orléans, FR;

Michael Lynch, Saint Jean de la Ruelle, FR;

Assignees:

LES LABORATOIRES SERVIER, Suresnes, FR;

SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY, Jing'an District, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 233/18 (2006.01); C07C 309/30 (2006.01); C07C 303/32 (2006.01); C07C 231/22 (2006.01);
U.S. Cl.
CPC ...
C07C 233/18 (2013.01); C07C 231/22 (2013.01); C07C 303/32 (2013.01); C07C 309/30 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention relates to new forms of co-crystals of agomelatine and p-toluenesulphonic acid, to a process for their preparation and to pharmaceutical compositions containing them. The co-crystals according to the invention have better solubility than agomelatine and are therefore more suitable for the preparation of pharmaceutical compositions. They also have better stability and purity and, moreover, are obtained by a simple process which does not include any difficult steps.


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