The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 30, 2017

Filed:

Apr. 22, 2014
Applicant:

Stryker European Holdings I, Llc, Kalamazoo, MI (US);

Inventors:

Mirjam Lilja, Farsta, SE;

Jan Henrik Sörensen, Kiel, DE;

Philip Procter, Divonne les Bains, FR;

Hartwig Steckel, Kiel, DE;

Torben Christian Sörensen, Mönkeberg, DE;

Assignee:

Stryker European Holdings I, LLC, Kalamazoo, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/32 (2006.01); A61L 31/16 (2006.01); A61C 8/00 (2006.01); A61L 27/54 (2006.01); A61L 31/08 (2006.01); A61C 19/06 (2006.01); C23C 4/12 (2016.01);
U.S. Cl.
CPC ...
A61L 31/16 (2013.01); A61C 8/0013 (2013.01); A61C 19/063 (2013.01); A61L 27/32 (2013.01); A61L 27/54 (2013.01); A61L 31/086 (2013.01); C23C 4/127 (2013.01);
Abstract

A method for loading a hydroxyapatite coated implant with a therapeutic agent including the steps of providing an implant and applying a hydroxyapatite coating on a surface of the implant. The hydroxyapatite coated implant is contacted with a solution including the therapeutic agent. The hydroxyapatite coated implant and solution is heated to temperature of about 60° C. to about 100° C. Pressure is applied to the hydroxyapatite coated implant and solution from about 2 bar to about 10 bar, to load the hydroxyapatite coated implant with the therapeutic agent. An implant made according to the method has sustained therapeutic agent delivery and includes a base and a biomimetic hydroxyapatite coating disposed on a surface thereof.


Find Patent Forward Citations

Loading…