The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 30, 2017

Filed:

Jul. 09, 2015
Applicant:

Worcester Polytechnic Institute, Worcester, MA (US);

Inventors:

Kevin G. Cornwell, Holliston, MA (US);

George D. Pins, Holden, MA (US);

Kristen Billiar, Worcester, MA (US);

Assignee:

WORCESTER POLYTECHNIC INSTITUTE, Worcester, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/14 (2015.01); C07K 14/00 (2006.01); A61L 27/22 (2006.01); A61L 31/04 (2006.01); A61K 38/36 (2006.01);
U.S. Cl.
CPC ...
A61L 27/225 (2013.01); A61K 38/363 (2013.01); A61L 31/046 (2013.01); A61L 2300/252 (2013.01); A61L 2400/04 (2013.01); A61L 2430/34 (2013.01);
Abstract

Compositions that include fibrin microthreads are provided. The compositions can include one or more therapeutic agents including cytokines and interleukins, extracellular matrix proteins and/or biologically active fragments thereof (e.g., RGD-containing peptides), hormones, vitamins, nucleic acids, chemotherapeutics, antibiotics, and cells. Also provided are methods of making compositions that include fibrin microthreads. Also provided are methods for using the compositions to repair or ameliorate damaged or defective organs or tissues.


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