The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2017
Filed:
Oct. 09, 2015
Applicant:
Thomas Jefferson University, Philadelphia, PA (US);
Inventors:
Scott A. Waldman, Ardmore, PA (US);
Michael S. Magee, Philadelphia, PA (US);
Adam E. Snook, Aston, PA (US);
Assignee:
Thomas Jefferson University, Philadelphia, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 47/48 (2006.01); C07K 16/40 (2006.01); G01N 33/574 (2006.01); G01N 33/573 (2006.01); A61K 49/00 (2006.01); A61K 51/10 (2006.01); A61K 35/17 (2015.01);
U.S. Cl.
CPC ...
A61K 47/48646 (2013.01); A61K 35/17 (2013.01); A61K 47/48384 (2013.01); A61K 47/48615 (2013.01); A61K 49/0058 (2013.01); A61K 51/1063 (2013.01); A61K 51/1075 (2013.01); C07K 16/40 (2013.01); G01N 33/573 (2013.01); G01N 33/57492 (2013.01); C07K 2317/622 (2013.01); G01N 2333/988 (2013.01);
Abstract
Antibodies and antigen-binding fragments of antibodies that bind GCC are disclosed. In some embodiments, the antibodies are humanized, chimeric or human. Nucleic acids and vectors encoding the antibodies or portions thereof, recombinant cells that contain the nucleic acids, and compositions comprising the antibodies or antigen-binding fragments are also disclosed. The invention also provides therapeutic and diagnostic methods utilizing the antibodies and antigen-binding.