The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 30, 2017

Filed:

Feb. 26, 2016
Applicant:

Mallinckrodt Llc, Hazelwood, MO (US);

Inventors:

William L. Neumann, Kirkwood, MO (US);

Richard B. Dorshow, St. Louis, MO (US);

John N. Freskos, Clayton, MO (US);

Karen L. Wooley, College Station, TX (US);

Nam S. Lee, College Station, TX (US);

Yun Lin, College Station, TX (US);

Guorong Sun, Bryan, TX (US);

Assignees:

Mallinckrodt LLC, Hazelwood, MO (US);

Washington University, St. Louis, MO (US);

The Texas A&M University System, College Station, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 41/00 (2006.01); A61K 9/107 (2006.01); A61K 9/51 (2006.01); A61K 49/00 (2006.01); A61K 9/14 (2006.01); A61K 31/20 (2006.01); A61K 31/70 (2006.01); A61K 38/16 (2006.01); A61K 38/22 (2006.01); A61K 39/395 (2006.01); A61M 5/00 (2006.01); A61K 31/055 (2006.01); A61K 31/325 (2006.01); A61K 31/337 (2006.01); A61K 31/704 (2006.01); A61K 38/08 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0057 (2013.01); A61K 9/0092 (2013.01); A61K 9/1075 (2013.01); A61K 9/146 (2013.01); A61K 9/5138 (2013.01); A61K 9/5192 (2013.01); A61K 31/055 (2013.01); A61K 31/20 (2013.01); A61K 31/325 (2013.01); A61K 31/337 (2013.01); A61K 31/70 (2013.01); A61K 31/704 (2013.01); A61K 38/08 (2013.01); A61K 38/16 (2013.01); A61K 38/22 (2013.01); A61K 39/395 (2013.01); A61K 49/0021 (2013.01); A61K 49/0054 (2013.01); A61K 49/0082 (2013.01); A61K 49/0093 (2013.01); A61M 5/007 (2013.01);
Abstract

The present invention provides optical agents comprising optically functional cross linked supramolecular structures and assemblies useful for tandem optical imaging and therapy. Supramolecular structures and assemblies of the present invention include optically functional shell-cross linked micelles wherein optical functionality is achieved via incorporation of one or more linking groups that include one or more photoactive moieties. The present invention further includes imaging and therapeutic methods using one or more optical agents of the present invention including optically functional shell cross-linked micelles having an associated therapeutic agent.


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