The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2017
Filed:
Feb. 04, 2016
Applicants:
National Yang-ming University, Taipei, TW;
National Taiwan University, Taipei, TW;
Inventors:
Zee-Fen Chang, Taipei, TW;
Jim-Min Fang, Taipei, TW;
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); C07D 513/04 (2006.01); A61K 31/704 (2006.01); C07D 519/00 (2006.01); C07D 275/04 (2006.01); C07F 7/18 (2006.01); A61K 31/695 (2006.01); C07D 417/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61K 31/695 (2013.01); A61K 31/704 (2013.01); C07D 275/04 (2013.01); C07D 417/04 (2013.01); C07D 513/04 (2013.01); C07D 519/00 (2013.01); C07F 7/1856 (2013.01);
Abstract
The present invention relates to novel TMPK inhibitor and their methods of use. In particular, it relates to novel TMPK inhibitor of Formula (I) and therapeutics that decrease the cellular dTTP level to suppress the growth and inhibit DNA repair in tumor cells and acts as a novel chemosensitizer, which are useful in methods for treating or preventing cancers.