The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 30, 2017

Filed:

Jun. 18, 2012
Applicants:

Sheldon Cao, San Diego, CA (US);

Janeta Popovici-muller, Windham, NH (US);

Francesco G. Salituro, Marlborough, MA (US);

Jeffrey O. Saunders, Lincoln, MA (US);

Xuefei Tan, Shanghai, CN;

Jeremy Travins, Southborough, MA (US);

Shunqi Yan, Irvine, CA (US);

Zhixiong YE, West Windsor, NJ (US);

Inventors:

Sheldon Cao, San Diego, CA (US);

Janeta Popovici-Muller, Windham, NH (US);

Francesco G. Salituro, Marlborough, MA (US);

Jeffrey O. Saunders, Lincoln, MA (US);

Xuefei Tan, Shanghai, CN;

Jeremy Travins, Southborough, MA (US);

Shunqi Yan, Irvine, CA (US);

Zhixiong Ye, West Windsor, NJ (US);

Assignee:

AGIOS PHARMACEUTICALS, INC, Cambridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 491/052 (2006.01); C07D 401/04 (2006.01); C07D 519/00 (2006.01); C07D 217/22 (2006.01); C07D 471/04 (2006.01); C07D 405/12 (2006.01); A61K 31/496 (2006.01); A61K 31/519 (2006.01); C07D 217/26 (2006.01); C07D 413/04 (2006.01); A61K 31/551 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61K 31/519 (2013.01); A61K 31/551 (2013.01); C07D 217/22 (2013.01); C07D 217/26 (2013.01); C07D 401/04 (2013.01); C07D 405/12 (2013.01); C07D 413/04 (2013.01); C07D 471/04 (2013.01); C07D 491/052 (2013.01); C07D 519/00 (2013.01);
Abstract

Provided are compounds of formula (I), wherein X, Y, Z, W, V, R, Rand m are defined as in the description. Their pharmaceutical compositions and their uses for treating cancers are also provided.


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