The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 30, 2017

Filed:

Mar. 08, 2012
Applicants:

Alexander Keith Stewart, Scottsdale, AZ (US);

Peter Bergsagel, Scottsdale, AZ (US);

Rafael Fonseca, Scottsdale, AZ (US);

Esteban Braggio, Scottsdale, AZ (US);

Inventors:

Alexander Keith Stewart, Scottsdale, AZ (US);

Peter Bergsagel, Scottsdale, AZ (US);

Rafael Fonseca, Scottsdale, AZ (US);

Esteban Braggio, Scottsdale, AZ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/454 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
A61K 31/454 (2013.01); G01N 33/57426 (2013.01); G01N 2800/52 (2013.01);
Abstract

This document provides methods and materials related to assessing responsiveness to lenalidomide, thalidomide, and/or other IMiDs (structural and functional analogues of thalidomide that represent a promising new class of immunomodulators). For example, methods and materials for using CRBN levels to determine whether or not cancer cells (e.g., multiple myeloma cells) are susceptible to lenalidomide, thalidomide, and/or other IMiDs are provided.


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