The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 30, 2017

Filed:

Dec. 16, 2015
Applicant:

University of Massachusetts, Boston, MA (US);

Inventors:

Gary R. Ostroff, Worcester, MA (US);

Ernesto Soto, Worcester, MA (US);

Assignee:

UNIVERSITY OF MASSACHUSETTS, Boston, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 9/16 (2006.01); A61K 9/50 (2006.01); A61K 9/51 (2006.01); A61K 47/48 (2006.01); B82Y 5/00 (2011.01); A61K 31/704 (2006.01); G01N 33/58 (2006.01); A61K 35/66 (2015.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1652 (2013.01); A61K 9/1682 (2013.01); A61K 9/5068 (2013.01); A61K 9/5115 (2013.01); A61K 31/704 (2013.01); A61K 47/489 (2013.01); A61K 47/48015 (2013.01); A61K 47/4823 (2013.01); A61K 47/4893 (2013.01); A61K 47/48853 (2013.01); B82Y 5/00 (2013.01); G01N 33/587 (2013.01); A61K 35/66 (2013.01); A61K 48/00 (2013.01);
Abstract

The present invention generally relates to yeast cell wall microparticles loaded with nanoparticles for receptor-targeted nanoparticle delivery. In particular, the present invention relates to trapping nanoparticles either on the surface or inside a yeast glucan particles, for example, yeast glucal particles. The present invention further relates to methods of making the yeast cell wall particles loaded with nanoparticles. The present invention also relates to methods of using the yeast cell wall particles loaded with nanoparticles for receptor-targeted delivery of the nanoparticles, e.g., drug containing nanoparticles.


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