The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 23, 2017

Filed:

Jun. 19, 2015
Applicant:

Celera Corporation, Alameda, CA (US);

Inventors:

Steve Ruben, Brookeville, MD (US);

Bruno Domon, Zurich, CH;

Candy Lee, Bethesda, MD (US);

Assignee:

Celera Corporation, San Clemente, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); G01N 33/68 (2006.01); C07K 14/47 (2006.01); C07K 16/18 (2006.01); C12N 15/113 (2010.01); C12Q 1/68 (2006.01); A61K 47/48 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57484 (2013.01); A61K 47/48538 (2013.01); C07K 14/47 (2013.01); C07K 16/18 (2013.01); C12N 15/113 (2013.01); C12Q 1/6886 (2013.01); G01N 33/574 (2013.01); G01N 33/57423 (2013.01); G01N 33/6893 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/54 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/622 (2013.01); C12N 2310/14 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/136 (2013.01); G01N 2500/10 (2013.01); Y10T 436/143333 (2015.01);
Abstract

Methods and compositions for diagnosing and treating diseases, particularly cancer, associated with differential expression of cancer-associated targets (CAT) in disease cells compared to healthy cells are provided. Also provided are antagonists and agonists of CAT, and methods for screening agents that modulate CAT level or activity in vivo or in vitro.


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