The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 23, 2017
Filed:
Nov. 04, 2015
Medicago, Inc., Sainte-Foy, Quèbec, CA;
Centre National DE LA Recherche Scientifique, Pars, FR;
Universite DE Rouen, Mont-Saint-Aignan, FR;
Thomas Paccalet, Rouen, FR;
Muriel Bardor, Mont Saint Aignan, FR;
Christophe Rihouey, Sainte-Foy, CA;
Véronique Gomord, Rouen, FR;
Loïc Faye, Saint-Jacques-sur-Darnétal, FR;
Patrice Lerouge, Grand Couronne, FR;
Stéphanie Aquin, Chavannes, CH;
Louis-Philippe Vezina, Neuville, CA;
Marc-André D'Aoust, Québec, CA;
Medicago Inc., Quebec, CA;
Centre National de la Recherche Scientifique, Paris, FR;
Universite De Rouen, Mont-Saint-Aignan, FR;
Abstract
A method of synthesizing sialic acid in plants, and plants capable of synthesizing sialic acid is provided. Furthermore, a method of producing sialylated protein in a plant is also provided. The method to synthesize sialic acid comprises providing a plant comprising a nucleotide sequence encoding N-acetyl neuraminic acid (Neu5Ac) synthase or Neu5Ac lyase, and expressing the nucleotide sequence thereby synthesizing sialic acid. The plant may also co-express a nucleotide sequence encoding one or more than one of an epimerase, a CMP-Neu5Ac synthase, a CMP-Neu5Ac transporter and a sialyltransferase.