The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 23, 2017

Filed:

Dec. 05, 2011
Applicants:

Hiroaki Suga, Tokyo, JP;

Takashi Higuchi, Tokyo, JP;

Inventors:

Hiroaki Suga, Tokyo, JP;

Takashi Higuchi, Tokyo, JP;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C40B 40/10 (2006.01); C12N 15/10 (2006.01); C12P 11/00 (2006.01); C12P 21/02 (2006.01); C07K 14/00 (2006.01); C07K 1/107 (2006.01); C07K 2/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1062 (2013.01); C07K 1/107 (2013.01); C07K 2/00 (2013.01); C07K 14/001 (2013.01); C12P 11/00 (2013.01); C12P 21/02 (2013.01); A61K 38/00 (2013.01); C40B 40/10 (2013.01);
Abstract

An object of the invention is to provide a peptide having a stabilized secondary structure. The present invention provides a peptide having a secondary structure stabilized by a crosslinked structure and containing at least one combination of a special amino acid of the formula (I): (wherein, (A) represents a single bond or a linking group having, in the main chain thereof, from 1 to 10 atoms; (B) represents a group containing at least one π bond; (C) represents a hydrogen atom or an alkyl group which may be substituted with a substituent; and X represents a group substitutable by a substitution reaction with a sulfanyl group) and an amino acid having, in the side chain thereof, a sulfanyl group; and having the crosslinked structure formed through a thioether bond between the side chain of the special amino acid residue and the sulfanyl group.


Find Patent Forward Citations

Loading…