The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9657057 B1

PDF
Full Text
Expired
Date of Patent:
May. 23, 2017

Filed:

Mar. 14, 2014
Applicant:

Onyx Therapeutics, Inc., South San Francisco, CA (US);

Inventors:

Dustin McMinn, Pacifica, CA (US);

Henry Johnson, San Bruno, CA (US);

David C. Moebius, Foster City, CA (US);

Assignee:

Onyx Therapeutics, Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/06 (2006.01); C07K 5/083 (2006.01); C07K 5/097 (2006.01); C07K 5/02 (2006.01); C07K 5/062 (2006.01); C07K 5/06 (2006.01); C07K 5/078 (2006.01); C07K 5/065 (2006.01); C07K 5/072 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 5/0806 (2013.01); A61K 38/06 (2013.01); C07K 5/0202 (2013.01); C07K 5/0205 (2013.01); C07K 5/06026 (2013.01); C07K 5/06069 (2013.01); C07K 5/06078 (2013.01); C07K 5/06121 (2013.01); C07K 5/06139 (2013.01); C07K 5/06147 (2013.01); C07K 5/06173 (2013.01); C07K 5/06191 (2013.01); C07K 5/0821 (2013.01); A61K 38/00 (2013.01);
Abstract

Provided herein are dipeptide and tripeptide epoxy ketone protease inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula (X): and pharmaceutically acceptable salts and compositions including the same. The compounds and compositions provided herein may be used, for example, in the treatment of proliferative diseases including cancer and autoimmune diseases.


Find Patent Forward Citations

McMinn, Dustin. (2017). Dipeptide and tripeptide epoxy ketone protease inhibitors (U.S. Patent No. 9657057). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9657057

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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