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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9657034 B1

PDFFull Text
Date of Patent:
May. 23, 2017

Filed:

Jan. 18, 2016

Substituted furo[3,2-c]pyridines, thieno[3,2-c]pyridines, thieno[2,3-d]pyridazines and pyrido[3,4-d]pyridazines as phosphodiesterase type 10a inhibitors

Applicants:

Abbvie Deutschland Gmbh & Co. KG, Wiesbaden, DE;

Abbvie Inc., North Chicago, IL (US);

Inventors:

Hervé Geneste, Ludwigshafen, DE;

Michael Ochse, Ludwigshafen, DE;

Karla Drescher, Ludwigshafen, DE;

Sean Turner, Ludwigshafen, DE;

Berthold Behl, Ludwigshafen, DE;

Loic Laplanche, Ludwigshafen, DE;

Jürgen Dinges, North Chicago, IL (US);

Clarissa Jakob, North Chicago, IL (US);

Lawrence Black, North Chicago, IL (US);

Katja Jantos, Ludwigshafen, DE;

Assignees:

AbbVie Deuschland GmbH & Co. KG, Wiesbaden, DE;

AbbVie Inc., North Chicago, IL (US);

Attorney:

Neal, Gerber & Eisenberg LLP

Primary Examiner:

Douglas M Willis

Int. Cl.
CPC ...
A61K 31/5025 (2006.01); A61K 31/4355 (2006.01); A61K 31/4365 (2006.01); C07D 487/04 (2006.01); C07D 491/048 (2006.01); C07D 495/04 (2006.01); C07D 519/00 (2006.01); C07D 401/14 (2006.01); C07D 401/06 (2006.01); C07D 471/04 (2006.01); C07D 417/14 (2006.01); C07D 413/14 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); C07D 401/06 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 491/048 (2013.01); C07D 495/04 (2013.01);
Abstract

The present invention relates to novel compounds of the formula I which are inhibitors of phosphodiesterase type 10A and to their use for the manufacture of a medicament and which thus are suitable for treating or controlling of medical disorders selected from neurological disorders and psychiatric disorders, for ameliorating the symptoms associated with such disorders and for reducing the risk of such disorders.

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