The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 23, 2017

Filed:

Dec. 22, 2011
Applicants:

Colleen Hudson, Malden, MA (US);

Timothy C. Barden, Salem, MA (US);

James Jia, Somerville, MA (US);

Ara Mermerian, Melrose, MA (US);

BO Peng, Arlington, MA (US);

Jane Yang, Boxborough, MA (US);

Xiang Y. Yu, Acton, MA (US);

Kevin Sprott, Needham, MA (US);

Angelika Fretzen, Somerville, MA (US);

Inventors:

Colleen Hudson, Malden, MA (US);

Timothy C. Barden, Salem, MA (US);

James Jia, Somerville, MA (US);

Ara Mermerian, Melrose, MA (US);

Bo Peng, Arlington, MA (US);

Jane Yang, Boxborough, MA (US);

Xiang Y. Yu, Acton, MA (US);

Kevin Sprott, Needham, MA (US);

Angelika Fretzen, Somerville, MA (US);

Assignee:

Ironwood Pharmaceuticals, Inc., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/444 (2006.01); A61K 31/4439 (2006.01); C07D 471/04 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); A61K 31/4045 (2006.01); A61K 31/497 (2006.01); A61K 31/501 (2006.01); A61K 31/506 (2006.01); A61K 45/06 (2006.01); C07D 209/14 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/4045 (2013.01); A61K 31/444 (2013.01); A61K 31/4439 (2013.01); A61K 31/497 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 45/06 (2013.01); C07D 209/14 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01);
Abstract

The present disclosure relates to compounds useful as inhibitors of the enzyme Fatty Acid Amide Hydrolase (FAAH). The disclosure also provides pharmaceutically acceptable compositions comprising the compounds of the disclosure and methods of using the compositions in the treatment or prevention of various disorders. Compounds of the invention are described in Table 1.


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