The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 23, 2017

Filed:

May. 04, 2016
Applicant:

Astrazeneca Ab, Sodertalje, SE;

Inventors:

Robert Ronn, Uppsala, SE;

Carl Jonas Lindh, Uppsala, SE;

Erik Ringberg, Uppsala, SE;

Hanna Birgitta Ellinor Andersson, Goteborg, SE;

Peter Nilsson, Stockholm, SE;

Wesley Ralph Schaal, Uppsala, SE;

Magnus Munck af Rosenschöld, Molndal, SE;

Antonios Nikitidis, Molndal, SE;

Grigorios Nikitidis, Molndal, SE;

Petra Johannesson, Molndal, SE;

Christian Tyrchan, Molndal, SE;

Assignee:

ASTRAZENECA AB, Sodertalje, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/12 (2006.01); C07D 405/12 (2006.01); A61K 31/44 (2006.01); A61K 31/4439 (2006.01); A61K 31/496 (2006.01); A61K 31/505 (2006.01); C07D 213/74 (2006.01); C07D 401/08 (2006.01); C07D 239/42 (2006.01); C07D 241/20 (2006.01); C07C 211/55 (2006.01); C07C 211/58 (2006.01); C07D 215/38 (2006.01); C07D 239/47 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); A61K 31/44 (2013.01); A61K 31/4439 (2013.01); A61K 31/496 (2013.01); A61K 31/505 (2013.01); C07C 211/55 (2013.01); C07C 211/58 (2013.01); C07D 213/74 (2013.01); C07D 215/38 (2013.01); C07D 239/42 (2013.01); C07D 239/47 (2013.01); C07D 241/20 (2013.01); C07D 401/08 (2013.01); C07D 401/12 (2013.01);
Abstract

There is provided compounds of formula I, wherein E, E, E, E, L, Y, Y, Y, Rand z have meanings provided in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene Csynthase is desired and/or required, and particularly in the treatment of respiratory diseases and inflammation.


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