The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 23, 2017

Filed:

Sep. 19, 2014
Applicant:

Shanghai Yingli Pharmaceutical Co., Ltd., Shanghai, CN;

Inventors:

Zusheng Xu, Shanghai, CN;

Yangtong Lou, Shanghai, CN;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 239/84 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 473/34 (2006.01); C07D 473/32 (2006.01); C07D 495/04 (2006.01); C07D 487/04 (2006.01); A61K 31/5377 (2006.01); A61K 31/498 (2006.01); A61K 31/635 (2006.01); A61K 31/4985 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 239/84 (2013.01); C07D 401/04 (2013.01); C07D 403/04 (2013.01); C07D 405/14 (2013.01); C07D 473/34 (2013.01); C07D 487/04 (2013.01); C07D 495/04 (2013.01);
Abstract

Disclosed are a fused heterocyclic compound, a preparation method therefor, a pharmaceutical composition, and uses thereof. The preparation method of the fused heterocyclic compound and/or the pharmaceutically acceptable salt thereof in the present invention comprises three synthesizing routes. The present invention also provides a pharmaceutical composition, containing one or more of the fused heterocyclic compound, the pharmaceutically acceptable salt, hydrates, solvent compounds, polymorphs and prodrugs thereof, and a pharmaceutically acceptable carrier. The present invention also relates to an application of the fused heterocyclic compound and/or the pharmaceutical composition in preparing kinase inhibitors and in preparing drugs for preventing and treating diseases related to kinase. The fused heterocyclic compound of the present invention has selective inhibition function on PI3K δ, and can be used for preparing drugs for preventing and treating cell proliferation diseases such as cancers, infections, inflammations, or autoimmune diseases.


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