The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 23, 2017
Filed:
Jul. 29, 2014
Shanghai Syncores Technologies Inc. Ltd., Shanghai, CN;
Zhejiang Huahai Pharmaceutical Co., Ltd., Zhejiang, CN;
Boyu Wang, Shanghai, CN;
Jinfeng Yao, Shanghai, CN;
Luning Huang, Shanghai, CN;
Jeannie Zhang, Shanghai, CN;
Shanghai Syncores Technologies Inc. Ltd., Shanghai, CN;
Zhejiang Huahai Pharmaceutical Co., Ltd., Zhejiang, CN;
Abstract
The invention relates to a method for synthesizing an intermediate of Apixaban comprising reacting a compound of formula I with 5-chloro-valeryl chloride in the presence of inorganic base in an inert solvent to obtain a compound of formula II, with the reaction formula of (A), wherein R is selected from nitro group and the group (B). The method is mild in reaction condition, simple in operation, easy in purification, inexpensive in production cost, environmental-friendly, and suitable for industrial production.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile