logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9656956 B1

PDFFull Text
Date of Patent:
May. 23, 2017

Filed:

Aug. 04, 2014

Benzene, pyridine, and pyridazine derivatives

Applicant:

Esanex, Inc., Indianapolis, IN (US);

Inventors:

Kenneth He Huang, Chapel Hill, NC (US);

Jeron Eaves, San Francisco, CA (US);

Gunnar Hanson, Bothell, WA (US);

James Veal, Apex, NC (US);

Thomas Barta, Carrboro, NC (US);

Lifeng Geng, Midlothian, VA (US);

Lindsay Hinkley, Lincoln University, PA (US);

Assignee:

Esanex, Inc., Indianapolis, IN (US);

Attorney:

McDonnell Boehnen Hulbert & Berghoff

Primary Examiner:

Golam M M Shameem

Assistant Examiner:

Laura Daniel

Int. Cl.
CPC ...
C07D 231/56 (2006.01); C07D 209/08 (2006.01); C07D 209/14 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); A61K 31/404 (2006.01); A61K 31/416 (2006.01); A61K 31/454 (2006.01); A61K 31/5377 (2006.01); A61K 45/00 (2006.01); A61N 5/10 (2006.01); C07D 231/54 (2006.01); C07D 413/12 (2006.01); A61K 31/4439 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 209/08 (2013.01); A61K 31/404 (2013.01); A61K 31/416 (2013.01); A61K 31/4439 (2013.01); A61K 31/454 (2013.01); A61K 31/5377 (2013.01); A61K 45/00 (2013.01); A61K 45/06 (2013.01); A61N 5/10 (2013.01); C07D 209/14 (2013.01); C07D 231/54 (2013.01); C07D 231/56 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01);
Abstract

Disclosed are compounds and pharmaceutically acceptable salts of Formula I wherein R, R, R, R, R, R, R, n, Q, Q, Q, Y, and X-Xare as defined herein. Compounds of Formula I are useful in the treatment of diseases and/or conditions related to cell proliferation, such as cancer, inflammation, arthritis, angiogenesis, or the like. Also disclosed are pharmaceutical compositions comprising compounds of the invention and methods of treating the aforementioned conditions using such compounds.

Find Patent Forward Citations

Loading…