The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9655999 B1

PDF
Full Text
Expired
Date of Patent:
May. 23, 2017

Filed:

Mar. 12, 2014
Applicant:

Carnegie Mellon University, Pittsburgh, PA (US);

Inventors:

Christopher J. Bettinger, Pittsburgh, PA (US);

Michael Bruce Horowitz, Jones Mills, PA (US);

Assignee:

Carnegie Mellon University, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61F 13/00 (2006.01); A61L 29/08 (2006.01); A61L 29/16 (2006.01); A61B 17/12 (2006.01); A61K 31/352 (2006.01); A61L 29/14 (2006.01); A61M 25/00 (2006.01); A61L 31/06 (2006.01); A61L 31/10 (2006.01); A61L 31/16 (2006.01);
U.S. Cl.
CPC ...
A61L 29/085 (2013.01); A61B 17/1215 (2013.01); A61B 17/12031 (2013.01); A61B 17/12113 (2013.01); A61B 17/12145 (2013.01); A61K 31/352 (2013.01); A61L 29/148 (2013.01); A61L 29/16 (2013.01); A61L 31/06 (2013.01); A61L 31/10 (2013.01); A61L 31/16 (2013.01); A61M 25/0045 (2013.01); A61L 2300/252 (2013.01); A61L 2300/602 (2013.01); A61L 2300/604 (2013.01); A61L 2420/04 (2013.01); A61L 2420/08 (2013.01); A61L 2430/36 (2013.01);
Abstract

A method is described herein for the treatment of intracranial aneurysms. The method comprises inserting into an aneurysm an embolism coil coated with a polymeric coating comprising a genipin, such as genipin or a derivative thereof, thereby increasing the stability of clots within the aneurysm. According to one example, the coating is a poly(L-lactide-co-glycolide) (PLGA) is used to release genipin to crosslink fibrin clots thereby creating more stable occlusions. Increased clotting can improve segregation of the weakened portion of the blood vessel from the rest of the vasculature and reduce the risk of recurrence.


Find Patent Forward Citations

Bettinger, Christopher. (2017). Coated vaso-occlusive device for treatment of aneurysms (U.S. Patent No. 9655999). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9655999

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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