The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 23, 2017
Filed:
May. 02, 2014
Applicant:
GE Healthcare Bio-sciences Corp., Piscataway, NJ (US);
Inventors:
Cynthia K. Lee, Needham, MA (US);
Thomas P. Monath, Harvard, MA (US);
Patrick M. Guertin, Mendon, MA (US);
Edward G. Hayman, Hanover, NH (US);
Assignee:
GE HEALTHCARE BIO-SCIENCES CORP., Piscataway, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); C12N 7/01 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); C12N 7/00 (2013.01); A61K 2039/5252 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/55566 (2013.01); C12N 2770/24121 (2013.01); C12N 2770/24134 (2013.01);
Abstract
The invention provides a an inactive, non-replicating vaccine comprising whole virion, chemically inactivated Yellow Fever virus which is inactivated using a method that ensures preservation of critical, neutralizing epitopes. The Yellow Fever virus has been adapted to propagate in cells to higher yields than the unadapted virus. The invention also provides methods for preventing Yellow Fever viral infection.